Journal of Clinical Research and Applied Medicine

Clinical Profile, Etiology, Management and Outcome of Patients with Acute Pancreatitis in a Tertiary Care Centre in North East India: A Three Years Retrospective Study

Wed, 28 Jun 2023 00:00:00 -0400

Background: Acute Pancreatitis is a very complex condition and common disease with wide clinical variation and with diverse local and systemic complications often requiring a hospital admission. Acute pancreatitis is an inflammatory process leading to abdominal pain, progressive destruction of exocrine tissue and in some patients a loss of endocrine tissue as well, with multiple organ failure and high mortality. Severity of acute pancreatitis is linked to the presence of comorbidities, systemic organ dysfunction and/or necrotizing pancreatitis. Aim and Objectives: The present study was aimed to study the clinical profile of acute pancreatitis, the etiology, complications, management and outcome of acute pancreatitis received treatment in the Department of Surgery, NEIGRIHMS, Shillong, Meghalaya, India. Materials and Methods: This is a hospital-based study by retrospective chart analysis of all acute pancreatic cases for the past 3 years which was conducted from January 2019 to December 2021. All patients with a diagnosis of acute pancreatitis were included in this study in order to find out the clinical presentations from the available clinical, laboratory and radiological data. Results: Of the 120 patients in this study, 96 were male and 4 were female. Minimum age in our study was 10 years and maximum were 70 years. Maximum numbers of patients were below 45 years of age. Alcohol was identified as the most important etiological factor associated with acute pancreatitis. Among the known etiological factors 87.5% of the cases were related to alcoholism and 12.5% were due to gall stone disease. Abdominal pain and vomiting were the most common symptoms in our study. Epigastric tenderness was present in 80.8% of the cases and guarding/rigidity in 50% of cases. 14.4% patients showed jaundice as a sign of acute pancreatitis. There was no major difference between the CT grading system and clinical grading system. Most of the patients recovered with conservative treatment, however percutaneous ultrasound guided aspiration and surgery were considered in very few selected cases as a last resort. Adverse outcome was noted in three patients with acute necrotizing pancreatitis having multiorgan failure and comorbidities. Conclusion: Acute pancreatitis is one of the leading causes of increase in morbidity and mortality to society. Clinical assessment along with radiological findings.

A Prospective Study of Drug Utilization Pattern in Patients from Orthopaedic Department in a Tertiary Care Teaching Hospital

Kajal K Valand, Sunil Piruwa, Pankaj K Chaudhary — Wed, 28 Jun 2023 00:00:00 -0400

Introduction: Drug utilization research was defined by WHO in 1977 as the marketing, distribution, prescription, and use of drugs in a society, with special emphasis on the resulting medical, social and economic consequence. Our objective of this study was to observe drug utilization pattern in patients from Orthopedic department IPD and OPD (Indoor and Outdoor Patients) in a teaching hospital. Materials and Methods: This was a prospective and observational study conducted on 100 Patients case file where study in orthopedic department IPD and OPD (Indoor and Outdoor Patients) of Dhiraj Hospital, Smt. Bhikhiben Kanjibhai Shah Medical Institute and Research Centre, Vadodara. Results: In our study a total of 100 Patients undergoing treatment with different kinds of drugs and it was observed that 58 numbers of patients (58%) were Male whereas 42 number of patients (42%) were female. 23% were diagnosed with pain in knee. It was noted that Maximum patients affected with co-morbidity were Diabetes Mellitus (53.33%). Total 230 (30.74%) drugs were prescribed with Generic name and 518 (69.25%) drugs were prescribed with Brand name. Ranitidine was most commonly prescribed drug i.e., in 74 patients (20.49%). The total average cost of drug treatment for IPD patients was Rs. 114261.07; Average cost per prescription for IPD patients was Rs. 1565.22. Average cost per prescription for OPD patients was Rs. 28120. 3. Average cost per prescription for OPD patients was Rs. 1041.49. Conclusion: Rational use of medicines is important in achieving standard healthcare services. Information on drug use research allows clinician to compare their approach to treat certain diseases. Therefore, current research work was useful to observe the prescribing pattern of drugs used in orthopedic department.

Role of Artificial Intelligence in Health Care Sector

R K Verma — Wed, 28 Jun 2023 00:00:00 -0400

INTRODUCTION

Artificial intelligence assumes a huge part in the medical services area, changing different parts of patient consideration, diagnostics, research, and regulatory errands. Here are a few critical jobs of artificial intelligence in medical care:

Clinical Imaging and Diagnostics

Man-made intelligence calculations can examine clinical pictures, for example, X-beams, CT outputs, and X-rays to aid the recognition and finding of illnesses. Computer based intelligence fueled indicative instruments can assist with distinguishing anomalies and give more precise and proficient judgments, empowering prior mediation and treatment.

Customized Medication

Artificial intelligence can investigate immense measures of patient information, including clinical records, genomic data, and way of life factors, to produce customized treatment plans. This assists medical care suppliers with fitting treatments to individual patients, further developing therapy results and decreasing unfriendly impacts. Read more . . .