Journal of Clinical Research and Applied Medicine <p style="user-select: auto;">The Journal of Clinical Research and Applied Medicine <strong style="user-select: auto;">(JCRAM</strong>) ISSN<strong>:</strong> 2583-0562 (Online), is a peer-reviewed, quarterly online journal aiming to communicate high-quality research articles, review articles, case studies, case series in the field of Medical Science (From Basic to Advanced research in all the fields of Medical science).</p> <p style="user-select: auto;"><strong style="user-select: auto;">JCRAM</strong> is open access, peer-reviewed and online journal that will encompass all aspects of basic research/clinical studies related to the field of Medical science. With the advancement of new technologies and the increasing expectation and demand from researchers, we are witnessing an enormous growth in clinical research. The journal seeks to promote research, exchange of scientific information, consideration of regulatory mechanisms that promote innovatory research in the field of Medical science. <strong style="user-select: auto;">JCRAM</strong> provides a platform for the exchange of new scientific information in the most precise and expeditious way to achieve timely dissemination of information and cross-fertilization of ideas. It is published quarterly and available in online versions.</p> <p style="user-select: auto;">The journal is Abstracted and Indexed in: Google Scholar, <a href="">Index Copernicus</a>, <a href="">SCILIT</a>.</p> <p style="user-select: auto;"><strong style="user-select: auto;"><u style="user-select: auto;">Scope of the journal</u></strong></p> <p style="user-select: auto;">Journal of Clinical Research and Applied Medicine (<strong style="user-select: auto;">JCRAM</strong>) aims to help students, researchers and scientists, worldwide to benefit from high-quality peer-reviewed articles and to their high performing works in the entire arena of Medical sciences. <strong style="user-select: auto;">JCRAM</strong> take much care in making your article published without much delay with your kind cooperation and support.</p> <p style="user-select: auto;">Original research papers, review articles, short communications, case studies, case series are welcomed provided they demonstrate new findings of relevance to the field as a whole. All articles will be peer-reviewed and will find a place in the Journal of Clinical Research and Innovation in Medicine (<strong style="user-select: auto;">JCRAM</strong>) based on the merit and innovativeness of the research work. <strong style="user-select: auto;">JCRAM</strong> hopes that Researchers, Research scholars, Academician, Industrialists, etc. would make use of this journal for the development of Medical science.</p> <p style="user-select: auto;"><span style="font-size: 0.875rem;"><strong style="user-select: auto;"><em style="user-select: auto;">Subjects Include</em></strong>:</span></p> <ul style="user-select: auto;"> <li style="user-select: auto;">Anatomy</li> <li style="user-select: auto;">Physiology</li> <li style="user-select: auto;">Biochemistry</li> <li style="user-select: auto;">Pharmacology</li> <li style="user-select: auto;">Pathology</li> <li style="user-select: auto;">Forensic Medicine</li> <li style="user-select: auto;">Microbiology</li> <li style="user-select: auto;">ENT</li> <li style="user-select: auto;">Ophthalmology</li> <li style="user-select: auto;">Preventive &amp; Social Medicine</li> <li style="user-select: auto;">Internal Medicine</li> <li style="user-select: auto;">Surgery</li> <li style="user-select: auto;">Obstetrics &amp; Gynecology</li> <li style="user-select: auto;">Pediatrics</li> <li style="user-select: auto;">Anesthesiology</li> <li style="user-select: auto;">Radiology</li> <li style="user-select: auto;">Skin &amp; VD</li> <li style="user-select: auto;">TB &amp; Chest</li> <li style="user-select: auto;">Psychiatry</li> <li style="user-select: auto;">Dentistry</li> <li style="user-select: auto;">Clinical Epidemiology</li> <li style="user-select: auto;">Biomedical Engineering</li> <li style="user-select: auto;">Orthopaedic</li> <li style="user-select: auto;">Pharmacy</li> <li style="user-select: auto;">Nursing/Paramedical</li> <li style="user-select: auto;">Digital Health</li> </ul> <p>Journal of Clinical Research and Applied Medicine, and its contents are licensed under a Creative Commons Attribution-Non-Commercial-No Derivs 4.0 License. Permissions beyond the scope of this license may be available with</p> en-US Journal of Clinical Research and Applied Medicine 2583-0562 <p>JCRAM and its contents are licensed under a Creative Commons Attribution-Non Commercial-No Derivs 4.0 License. Permissions beyond the scope of this license may be available with <a href=""></a></p> Estimation of Vitamin D Level in Severe Variant of TB against Less Severe Variant of TB in Paediatric Patients: A Comparative Study <p style="text-align: justify;"><strong>Background:</strong> Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis killing nearly 2 million people every year. In India, over 100,000 children die from tuberculosis every year. The best-understood function of Vitamin D is in the absorption of calcium from the small intestine, which helps to prevent diseases such as osteoporosis and osteomalacia in adults and rickets in children. The present study was done with an aim to estimate the level of Vitamin D in severe against less severe paediatric tuberculosis patients. <strong>Materials and Methods: </strong>This present prospective observational study was conducted in Department of TB and Chest of GMC, Azamgarh from February 2022 to March 2023 after approval from Ethical Committee GMC, Azamgarh. The study was done till the sample size of 96 patients was achieved in children up-to 18 years of age presenting with tuberculosis at our hospital. <strong>Results: </strong>Out of total 96 patients, 63 (53.23%) were male and 33 (46.77%) were female. Majority of patients were age group of &gt;10 years. 33 (46.77%) of them had positive history of contact, 63 (53.23%) had no history of contact. Majority 53 (85.48%) of TB were diagnosed through CBNAAT. Most common presentation was pulmonary TB (43.75%). 53 (55.20%) patients were having deficient Vit D. 26 (27.08%) had severe variant of TB and 70 (72.91%) had less-severe TB. Mean + SD level of serum Vitamin D3 in severe variant of TB was 13.4 + 7.8 and 22.6 + 8.9 in less-severe variant TB. Hypovitaminosis D was seen in 53 (55.20%) TB patients in which majority of case were of pulmonary TB 31(60.78%). 13 (13.54%) were in the age group 0-5 years, 24 (25%) were in the age group 5-10 years and 59 (61.45%) were of age &gt;10 years.<strong> Conclusion: </strong>The study findings support the assumption that hypovitaminosis D potentiates susceptibility to TB. This relationship should be investigated further in a large-cohort longitudinal study. We advocate for longitudinal studies across various geographical regions to accurately define the roles of Vitamin D on TB treatment and prevention.</p> Sunil Piruwa Ishrat Ali Ansari Pankaj K Chaudhary Copyright (c) 2023 Journal of Clinical Research and Applied Medicine 2023-11-02 2023-11-02 3 3 37 42 10.5530/jcram.3.3.8 Understanding the Link Between Social Media Use and Mental Health Issues <p>This article explores the&nbsp;connection between social media use and mental health, with an emphasis on the potential negative consequences and techniques for promoting positive well- being. It examines previous research on the psychological factors underlying social media's impact on mental health, such as social comparison, FOMO, cyberbullying, and online social support. The article additionally highlights vulnerable demographics, such as teenagers, young adults, and people with pre-existing mental health disorders, who may be especially prone to social media's harmful consequences. It emphasises the significance of responsible social media use and moderation in reducing negative outcomes and suggests viable interventions, legislation, and recommendations to develop a better digital environment that promotes mental well-being.</p> Mohammed Yunus Copyright (c) 2023 Journal of Clinical Research and Applied Medicine 2023-11-02 2023-11-02 3 3 31 36 10.5530/jcram.3.3.7